Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4143119 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2NPSR1NPC1LMNARAB9A | |
| SCHEMBL4156216 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2NPSR1NPC1LMNARAB9A | |
| SCHEMBL10384247 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2NPSR1NPC1LMNARAB9A | |
| SCHEMBL29840690 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2NPSR1NPC1LMNARAB9A | |
| SCHEMBL1777203 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2NPSR1NPC1LMNARAB9A | |
| SCHEMBL5441890 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2NPSR1NPC1LMNARAB9A | |
| SCHEMBL16306933 | 0.81 | LMNA (0.57) | SMN1; SMN2NPSR1NPC1LMNARAB9A | |
| SCHEMBL15025770 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1NPC1LMNARAB9A | |
| SCHEMBL1459228 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2NPSR1NPC1LMNARAB9A | |
| SCHEMBL10482310 | 0.78 | PTGDR2 (0.57) | SMN1; SMN2NPSR1CYSLTR2CYSLTR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101346346-B | Amine compound and use thereof for medical purposes | MITSUBISH TANABE PHARMA CORP | 2012-08-22 | — | — | CN | disclosed |
| CN-101346346-A | Amine compound and use thereof for medical purposes | MITSUBISH TANABE PHARMA CORP (JP) | 2009-01-14 | — | — | CN | disclosed |