Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 3/20 | 0.30 |
| ▸ | CDK9 | P50750 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064841 | 0.86 | HSP90AB1 (0.44) | CA1CA2CA7MAPK1HTT | |
| SCHEMBL27570091 | 0.83 | LMNA (0.44) | CA1CA2CA7CA13HSP90AB1 | |
| SCHEMBL4467853 | 0.81 | CA1 (0.37) | CA1CA2CA7CA13HSP90AB1 | |
| SCHEMBL1060727 | 0.81 | CA1 (0.38) | CA1CA2CA7MAPK1HTT | |
| SCHEMBL1065963 | 0.79 | HSP90AB1 (0.45) | CA1CA2CA7MAPK1HTT | |
| SCHEMBL4487332 | 0.79 | CA1 (0.36) | CA1CA2CA7HTTCA13 | |
| SCHEMBL4475432 | 0.77 | MAPT (0.35) | CA1CA2CA7MAPK1HTT | |
| SCHEMBL4391958 | 0.76 | HSP90AB1 (0.44) | MAPK1HTTHSP90AB1SRCABL1 | |
| SCHEMBL1063918 | 0.75 | HSP90AB1 (0.43) | CA1CA2CA7MAPK1HTT | |
| SCHEMBL4479224 | 0.75 | CA1 (0.47) | CA1CA2CA7MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101360497-A | Novel methods and formulations | GLAXO GROUP LTD (GB) | 2009-02-04 | — | — | CN | disclosed |