Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TACR3 | P29371 | 8/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2372595 | 0.90 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL27669534 | 0.85 | DHODH (0.61) | LMNATACR3PDE10ATSHRTP53 | |
| SCHEMBL14115125 | 0.84 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL3633684 | 0.84 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL4666988 | 0.81 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL8268500 | 0.80 | TACR3 (0.52) | SMN1; SMN2MEN1KMT2ATACR3PDE10A | |
| SCHEMBL4230222 | 0.80 | DHODH (0.70) | LMNASMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL2372674 | 0.80 | PDE10A (0.73) | LMNASMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL4668037 | 0.79 | TACR3 (0.53) | SMN1; SMN2MEN1KMT2ATACR3DHODH | |
| SCHEMBL2373281 | 0.79 | KDM4E (0.55) | LMNASMN1; SMN2MEN1KMT2ATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370782-A | Alkylsulphonamide quinolines | ASTRAZENECA AB (SE) | 2009-02-18 | — | — | CN | disclosed |