Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773039 | 1.00 | KDM4A (0.43) | KDM4AKDM4CSIGMAR1TMEM97PPARG | |
| SCHEMBL2771476 | 0.87 | CD274 (0.42) | PPARGF2PRSS1MEP1BKMT2A | |
| SCHEMBL2771473 | 0.87 | CD274 (0.42) | PPARGF2PRSS1MEP1BKMT2A | |
| SCHEMBL9968931 | 0.84 | NOS1 (0.39) | SIGMAR1TMEM97F2PRSS1 | |
| SCHEMBL407531 | 0.83 | SLC7A5 (0.39) | SIGMAR1SMN1; SMN2F2PRSS1MEP1B | |
| SCHEMBL9968916 | 0.83 | SLC7A5 (0.39) | SIGMAR1SMN1; SMN2F2PRSS1MEP1B | |
| SCHEMBL407530 | 0.83 | SLC7A5 (0.39) | SIGMAR1SMN1; SMN2F2PRSS1MEP1B | |
| SCHEMBL12505623 | 0.81 | MEN1 (0.54) | KMT2AMEN1RAB9A | |
| SCHEMBL12505590 | 0.81 | MEN1 (0.54) | KMT2AMEN1RAB9A | |
| SCHEMBL12505591 | 0.81 | MEN1 (0.54) | KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193125-A2 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009043889-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2009-04-09 | — | — | WO | disclosed |