Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666248 | 0.92 | TRPV1 (0.42) | TRPV1TRPA1SPHK1THRBGABRP | |
| SCHEMBL3400627 | 0.83 | — | — | |
| SCHEMBL8133063 | 0.79 | TRPV1 (0.39) | TRPV1TRPA1SPHK1THRBGABRP | |
| SCHEMBL1132328 | 0.79 | TRPV1 (0.44) | TRPV1TRPA1SPHK1 | |
| SCHEMBL16538719 | 0.79 | TRPV1 (0.39) | TRPV1TRPA1SPHK1THRBGABRP | |
| SCHEMBL8655511 | 0.78 | THRB (0.36) | TRPV1TRPA1THRBALDH1A1TDP1 | |
| SCHEMBL18541628 | 0.78 | THRB (0.36) | TRPV1TRPA1THRBTDP1LMNA | |
| SCHEMBL22321690 | 0.78 | THRB (0.36) | TRPV1TRPA1THRBTDP1LMNA | |
| SCHEMBL283758 | 0.78 | THRB (0.36) | TRPV1TRPA1THRBALDH1A1TDP1 | |
| SCHEMBL3949692 | 0.78 | THRB (0.36) | TRPV1TRPA1THRBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101233144-A | Stable nad/nadh derivatives | HOFFMANN LA ROCHE (CH) | 2008-07-30 | — | — | CN | disclosed |