Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL27730825 | 0.97 | ALDH1A1 (0.40) | ALDH1A1LMNATDP1MEN1USP2 | |
| Diethanolamine SCHEMBL1134213 | 0.97 | ALDH1A1 (0.40) | ALDH1A1LMNATDP1MEN1USP2 | |
| Isopropyl Alcohol SCHEMBL29874597 | 0.87 | CA12 (0.48) | ALDH1A1LMNATDP1MEN1MAPT | |
| Diethanolamine SCHEMBL8017895 | 0.85 | TDP1 (0.59) | ALDH1A1LMNATDP1MEN1USP2 | |
| Isopropyl Alcohol SCHEMBL26112219 | 0.84 | CA12 (0.50) | ALDH1A1LMNATDP1MEN1MAPT | |
| Diethanolamine SCHEMBL359260 | 0.83 | — | — | |
| Diethanolamine SCHEMBL31457586 | 0.83 | — | — | |
| Diethanolamine SCHEMBL29165291 | 0.82 | TSHR (0.56) | ALDH1A1LMNATDP1MEN1USP2 | |
| Diethanolamine SCHEMBL2803527 | 0.82 | TP53 (0.52) | ALDH1A1MEN1USP2MAPTKMT2A | |
| Diethanolamine SCHEMBL27908425 | 0.80 | TDP1 (0.38) | ALDH1A1LMNATDP1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101581891-B | Toner, image forming apparatus, image forming method, and process cartridge using the toner | RICOH CO LTD | 2012-09-26 | — | — | CN | disclosed |
| CN-101473273-B | Toner and image forming method | RICOH CO LTD | 2012-06-27 | — | — | CN | disclosed |
| CN-101692157-A | Toner, image forming apparatus, image forming method and process cartridge | RICOH KK | 2010-04-07 | — | — | CN | disclosed |
| CN-101581891-A | Toner, image forming apparatus, image forming method, and process cartridge using the toner | RICOH KK (JP) | 2009-11-18 | — | — | CN | disclosed |
| CN-101473273-A | Image forming apparatus, image forming method, and process cartridge | RICOH KK (JP) | 2009-07-01 | — | — | CN | disclosed |
| CN-101357982-A | Promoter for polycondensation reaction | KAO CORP (JP) | 2009-02-04 | — | — | CN | disclosed |