Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27711251 | 1.00 | CNR2 (0.44) | CNR2MEN1KMT2APDE10APDK1 | |
| SCHEMBL10744679 | 0.92 | PDE10A (0.41) | CNR2PDE10ADRD3HTTRAB9A | |
| Hydrochloric Acid SCHEMBL10744957 | 0.90 | PDE10A (0.40) | CNR2PDE10ADRD3HTTRAB9A | |
| SCHEMBL2293592 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2ADRD3ALDH1A1 | |
| SCHEMBL2297157 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2ADRD3ALDH1A1 | |
| SCHEMBL2294210 | 0.79 | MOGAT2 (0.35) | CNR2EPHX2DRD3ALDH1A1 | |
| SCHEMBL2294754 | 0.79 | MOGAT2 (0.35) | CNR2EPHX2DRD3ALDH1A1 | |
| SCHEMBL2292653 | 0.79 | PDE10A (0.42) | CNR2MEN1KMT2APDE10ADRD3 | |
| SCHEMBL2293475 | 0.79 | PDE10A (0.42) | CNR2PDE10ADRD3 | |
| SCHEMBL2299017 | 0.79 | PDE10A (0.42) | CNR2MEN1KMT2APDE10ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | claimed |
| CN-102120741-A | Production method of an optically active compound | MITSUBISHI TANABE PHARMA CORP | 2011-07-13 | — | — | CN | disclosed |
| CN-102050820-A | Preparation method of compound with optical activity | MITSUBISHI TANABE PHARMA CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-101228142-A | Intermediate compounds for the synthesis of pharmaceutical preparations, and process for their preparation | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-07-23 | — | — | CN | disclosed |