SCHEMBL2773258

SCHEMBL2773258

Cc1csc(C(=O)CCCl)c1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.55
GSK3B P49841 11/20 0.50
KDR P35968 2/20 0.37
CASP3 P42574 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP6 Q9GZR1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15979699 0.88 DAO (0.63) DAOGSK3BKDRCASP3SENP7
SCHEMBL6790693 0.86 GSK3B (0.66) DAOGSK3BKDRMAPTNPSR1
SCHEMBL28474265 0.83 DAO (0.57) DAOGSK3BKDRCASP3SENP7
SCHEMBL15979708 0.82 DAO (0.52) DAOGSK3BKDRCASP3SENP7
SCHEMBL6917802 0.81 DAO (0.60) DAOGSK3BNPSR1
SCHEMBL3867877 0.81 DAO (0.55) DAOGSK3BKDRCASP3SENP7
SCHEMBL15979698 0.80 GSK3B (0.62) DAOGSK3BKDRCASP3SENP7
SCHEMBL3752532 0.79 DAO (0.61) DAOGSK3BKDRCASP3SENP7
SCHEMBL15547606 0.77 DAO (0.59) DAOGSK3BKDRCASP3SENP7
SCHEMBL26970953 0.77 DAO (0.59) DAOGSK3BKDRCASP3SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2230243-A1 Pharmaceutical compounds Neuroscienze Pharmaness S.C. A R.L. (IT) 2010-09-22 EP disclosed
EP-2230243-A1 Pharmaceutical compounds Neuroscienze Pharmaness S.C. A R.L. (IT) 2010-09-22 EP disclosed
US-20100215759-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C.A.R.L. (IT) 2010-08-26 US disclosed
US-20100215759-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C.A.R.L. (IT) 2010-08-26 US disclosed
US-20100215759-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C.A.R.L. (IT) 2010-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100215759-A1 PHARMACEUTICAL COMPOUNDS CNR2, CNR1, OPRK1 DAO 2816/4885GSK3B 1828/4885KDR 305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.