Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | COMT | P21964 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30553888 | 0.98 | MAPK1 (0.68) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL2459763 | 0.98 | MAPK1 (0.68) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL4108644 | 0.96 | MAPK1 (0.66) | MAPK1CA1CA2CA9KDM4E | |
| Hydrochloric Acid SCHEMBL7525174 | 0.96 | MAPK1 (0.66) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL31440873 | 0.84 | KDM4E (0.56) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL28348888 | 0.83 | KDM4E (0.54) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL7180056 | 0.81 | MAPK1 (0.70) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL27592567 | 0.81 | MAPK1 (0.70) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL11679037 | 0.79 | MAPK1 (0.68) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL50688 | 0.79 | MAPK1 (1.00) | MAPK1CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |