Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | PPARA | Q07869 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713461 | 0.95 | PPARG (0.50) | NOTUMPPARGPPARALMNATSHR | |
| SCHEMBL27733653 | 0.88 | PPARG (0.47) | NOTUMPPARGPPARALMNAPPARD | |
| SCHEMBL27713299 | 0.84 | PPARG (0.48) | NOTUMPPARGPPARAPPARD | |
| SCHEMBL3527552 | 0.83 | PPARG (0.57) | NOTUMPPARGPPARALMNATSHR | |
| SCHEMBL27733822 | 0.82 | PPARG (0.45) | PPARGPPARAPPARD | |
| SCHEMBL3523095 | 0.79 | PPARG (0.65) | NOTUMPPARGPPARALMNATSHR | |
| SCHEMBL27713773 | 0.79 | PPARG (0.53) | PPARGPPARAPPARD | |
| SCHEMBL28775104 | 0.78 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL27733652 | 0.77 | NOTUM (0.46) | NOTUMLMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL28775088 | 0.77 | PPARG (0.54) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |