Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733953 | 0.89 | NOTUM (0.43) | NOTUMLMNATSHRHTTGAA | |
| SCHEMBL27733718 | 0.84 | KCNH2 (0.39) | HTR6MAPT | |
| SCHEMBL27713347 | 0.81 | TRPM8 (0.38) | — | |
| SCHEMBL28791617 | 0.80 | HTR6 (0.35) | SMN1; SMN2HTR6POLB | |
| SCHEMBL27910315 | 0.80 | HTR6 (0.37) | HTR6 | |
| SCHEMBL28770874 | 0.78 | ALDH1A1 (0.35) | SMN1; SMN2 | |
| SCHEMBL27733892 | 0.78 | TP53 (0.35) | SMN1; SMN2RAB9AMAPT | |
| SCHEMBL27713453 | 0.78 | AKR1B1 (0.34) | SMN1; SMN2POLBRAB9AMAPT | |
| SCHEMBL27733685 | 0.78 | PPARG (0.37) | HTR6POLBRAB9A | |
| SCHEMBL27733722 | 0.77 | NOTUM (0.48) | NOTUMLMNATSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |