Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | C5 | P01031 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733841 | 0.89 | F7 (0.36) | PTGS2F7LTA4HF3AHR | |
| SCHEMBL27733784 | 0.87 | PSEN1 (0.42) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL27713457 | 0.86 | PSEN1 (0.46) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL27713686 | 0.85 | PPARG (0.41) | MEN1KMT2APHGDHPSEN1PSEN2 | |
| SCHEMBL28775103 | 0.84 | MEN1 (0.41) | MEN1KMT2APHGDHPSEN1PSEN2 | |
| SCHEMBL27713338 | 0.83 | PSEN1 (0.40) | PTGS2MEN1ABCC4C5MAPT | |
| SCHEMBL28770821 | 0.82 | PTGS2 (0.39) | PTGS2PHGDHPSEN1PSEN2APH1B | |
| SCHEMBL27713495 | 0.81 | AKR1C3 (0.41) | PHGDHPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28775092 | 0.81 | AKR1C3 (0.39) | PTGS2PHGDHPSEN1PSEN2APH1B | |
| SCHEMBL27733659 | 0.81 | PSEN1 (0.38) | PTGS2PHGDHPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |