Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713301 | 0.89 | ACLY (0.43) | SMN1; SMN2ALDH1A1MAPTRECQLHPGD | |
| SCHEMBL27713335 | 0.84 | PPARG (0.58) | ALDH1A1RECQLHPGDHSD17B10ACLY | |
| SCHEMBL27733700 | 0.83 | RECQL (0.56) | ALDH1A1MAPTRECQLHPGDLMNA | |
| SCHEMBL27713493 | 0.83 | PPARG (0.43) | ALDH1A1MAPTRECQLLMNAHDAC3 | |
| SCHEMBL27733864 | 0.83 | PPARG (0.59) | RECQLACLYPPARGPPARAPPARD | |
| SCHEMBL27713452 | 0.82 | PPARG (0.58) | RECQLACLYPPARGPPARAPPARD | |
| SCHEMBL27733789 | 0.80 | PPARG (0.59) | MAPTRECQLPPARGPPARAPPARD | |
| SCHEMBL27733713 | 0.77 | PPARG (0.46) | RECQLHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27713297 | 0.77 | PPARG (0.50) | ACLYPPARGPPARAPPARD | |
| SCHEMBL27713308 | 0.75 | PPARG (0.40) | ALDH1A1RECQLHPGDKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |