Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27758186 | 0.81 | GAA (0.76) | CCR3GAAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8251054 | 0.79 | CCR3 (0.81) | CCR3GAAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2004615 | 0.79 | CCR3 (1.00) | CCR3GAAALDH1A1MEN1KMT2A | |
| SCHEMBL6153469 | 0.78 | GAA (0.80) | CCR3GAAALDH1A1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9593442 | 0.78 | CXCR4 (0.53) | CCR3 | |
| Hydrochloric Acid SCHEMBL10549658 | 0.78 | CXCR4 (0.53) | CCR3 | |
| SCHEMBL8191786 | 0.77 | CCR3 (0.96) | CCR3GAAALDH1A1MEN1KMT2A | |
| SCHEMBL7977320 | 0.77 | CCR3 (0.96) | CCR3GAAALDH1A1MEN1KMT2A | |
| SCHEMBL6156526 | 0.77 | GAA (0.70) | CCR3GAAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22549603 | 0.77 | CCR3 (0.77) | CCR3GAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101341125-B | New phenanthridine derivatives as bradykinin antagonists | RICHTER GEDEON NYRT | 2012-10-10 | — | — | CN | disclosed |
| CN-101341125-A | New phenanthridine derivatives as bradykinin antagonists | RICHTER GEDEON NYRT (HU) | 2009-01-07 | — | — | CN | disclosed |