Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 17/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.68 |
| ▸ | KIT | P10721 | 1/20 | 0.68 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713844 | 0.91 | FLT3 (0.69) | FLT3PDGFRBKIT | |
| SCHEMBL27734124 | 0.89 | FLT3 (0.67) | FLT3PDGFRBKITKDR | |
| SCHEMBL27734121 | 0.89 | FLT3 (0.59) | FLT3PDGFRBKIT | |
| SCHEMBL28775244 | 0.87 | FLT3 (0.66) | FLT3PDGFRBKITKDR | |
| SCHEMBL27734122 | 0.86 | FLT3 (0.72) | FLT3PDGFRBKIT | |
| SCHEMBL27734330 | 0.86 | FLT3 (0.67) | FLT3PDGFRBKIT | |
| SCHEMBL27713822 | 0.83 | FLT3 (0.69) | FLT3PDGFRBKITKDR | |
| SCHEMBL27734244 | 0.81 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL13956852 | 0.81 | FLT3 (1.00) | FLT3PDGFRBKIT | |
| SCHEMBL5135470 | 0.81 | FLT3 (0.55) | FLT3PDGFRBKITKDRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242843-A | Aminopyrimidines as kinase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |