Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 17/20 | 0.67 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775244 | 0.89 | FLT3 (0.66) | FLT3KITPDGFRBEGFRERBB2 | |
| SCHEMBL27734124 | 0.87 | FLT3 (0.67) | FLT3KITPDGFRBEGFRERBB2 | |
| SCHEMBL27734245 | 0.86 | FLT3 (0.68) | FLT3KITPDGFRB | |
| SCHEMBL27713822 | 0.84 | FLT3 (0.69) | FLT3KITPDGFRB | |
| SCHEMBL13956850 | 0.82 | FLT3 (0.55) | FLT3KITPDGFRBEGFRERBB2 | |
| SCHEMBL5135470 | 0.82 | FLT3 (0.55) | FLT3KITPDGFRBEGFRERBB2 | |
| SCHEMBL27713850 | 0.81 | FLT3 (0.70) | FLT3KITPDGFRBEGFRERBB2 | |
| SCHEMBL13956707 | 0.80 | FLT3 (1.00) | FLT3KITPDGFRB | |
| SCHEMBL27734328 | 0.80 | FLT3 (1.00) | FLT3KITPDGFRB | |
| Tert-Butyl Formate SCHEMBL28077893 | 0.79 | FLT3 (0.52) | FLT3KITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242843-A | Aminopyrimidines as kinase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-13 | — | — | CN | disclosed |