Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607197 | 1.00 | GAA (0.66) | GAAATMSLC1A3SLC1A2SLC7A5 | |
| SCHEMBL27734522 | 0.85 | SLC1A3 (0.50) | GAASLC1A3SLC1A2SLC7A5PKM | |
| SCHEMBL5607874 | 0.85 | SLC1A3 (0.50) | GAASLC1A3SLC1A2SLC7A5PKM | |
| SCHEMBL31689445 | 0.83 | GAA (0.52) | GAAATMSLC1A3SLC1A2PKM | |
| SCHEMBL5607232 | 0.81 | PGR (0.64) | SLC1A3SLC1A2PKMLMNAHDAC1 | |
| SCHEMBL27754835 | 0.81 | PGR (0.64) | SLC1A3SLC1A2PKMLMNAHDAC1 | |
| SCHEMBL7896707 | 0.81 | GAA (0.45) | GAAATMSLC1A3SLC1A2SLC7A5 | |
| SCHEMBL19234913 | 0.81 | HDAC1 (0.62) | GAASLC7A5PKMPTGS1ALPI | |
| SCHEMBL20715878 | 0.81 | HDAC1 (0.62) | GAASLC7A5PKMPTGS1ALPI | |
| SCHEMBL5078465 | 0.81 | HDAC1 (0.62) | GAASLC7A5PKMPTGS1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | claimed |
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | disclosed |