SCHEMBL27734802

SCHEMBL27734802

CCCCCc1ccc(Oc2ncnc(OC3CCN(C(=O)O)CC3)c2C)c(C)n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL391008 0.89 GPR119 (0.73) GPR119
SCHEMBL5052529 0.86 GPR119 (0.61) GPR119
SCHEMBL3170732 0.84 GPR119 (0.57) GPR119
SCHEMBL1067271 0.82 GPR119 (0.62) GPR119
SCHEMBL5045858 0.78 GPR119 (0.56) GPR119
SCHEMBL388732 0.78 GPR119 (0.76) GPR119
SCHEMBL15388540 0.78 GPR119 (0.76) GPR119
SCHEMBL390424 0.77 GPR119 (0.75) GPR119
SCHEMBL3162281 0.77 GPR119 (0.54) GPR119
SCHEMBL3810878 0.73 GPR119 (0.39) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101332303-A Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood glp-1 level ARENA PHARM INC (US) 2008-12-31 CN disclosed