Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.56 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27755799 | 0.83 | EGLN1 (0.49) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL27755810 | 0.83 | EGLN1 (0.45) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL4407134 | 0.73 | EGLN1 (0.63) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522744 | 0.72 | EGLN1 (1.00) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL29390250 | 0.72 | EGLN1 (1.00) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522787 | 0.72 | EGLN1 (0.65) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522788 | 0.71 | EGLN1 (0.72) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL27773936 | 0.70 | EGLN1 (0.59) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL2015310 | 0.70 | EGLN1 (0.59) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL28912438 | 0.70 | EGLN1 (0.59) | EGLN1BBOX1FTOTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101394843-A | Improved anemia treatment using HIF alpha stabilizers | FIBROGEN INC (US) | 2009-03-25 | — | — | CN | disclosed |