Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.59 |
| ▸ | BBOX1 | O75936 | 6/20 | 0.59 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.59 |
| ▸ | THRA | P10827 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570243 | 0.84 | THRA (0.70) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL28558839 | 0.83 | EGLN1 (0.45) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL2015310 | 0.79 | EGLN1 (0.59) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL4407134 | 0.78 | EGLN1 (0.63) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL2017928 | 0.78 | EGLN1 (0.58) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL25934724 | 0.78 | EGLN1 (0.80) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522620 | 0.77 | EGLN1 (0.69) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL4082616 | 0.76 | EGLN1 (0.76) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL523025 | 0.76 | EGLN1 (0.67) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL27773936 | 0.76 | EGLN1 (0.59) | EGLN1BBOX1FTOTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689635-B | 1, 7-naphthyridine derivative and preparation method and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-112689635-A | 1, 7-naphthyridine derivative and preparation method and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2021-04-20 | — | — | CN | disclosed |