Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.54 |
| ▸ | CES1 | P23141 | 7/20 | 0.51 |
| ▸ | FAAH2 | Q6GMR7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778444 | 0.85 | FAAH (0.61) | FAAHCES1FAAH2 | |
| SCHEMBL2772835 | 0.84 | CES1 (0.67) | FAAHCES1 | |
| SCHEMBL2775564 | 0.84 | FAAH (0.54) | FAAHCES1FAAH2 | |
| SCHEMBL2775030 | 0.82 | FAAH (0.70) | FAAHCES1 | |
| SCHEMBL2783334 | 0.81 | FAAH (0.54) | FAAHCES1FAAH2 | |
| SCHEMBL2773531 | 0.80 | FAAH (0.80) | FAAHCES1FAAH2 | |
| SCHEMBL2780980 | 0.77 | FAAH (0.57) | FAAHCES1FAAH2 | |
| SCHEMBL2784843 | 0.77 | FAAH (0.57) | FAAHCES1FAAH2 | |
| SCHEMBL2830349 | 0.77 | FAAH (0.58) | FAAHCES1FAAH2 | |
| SCHEMBL2785431 | 0.77 | HDAC3 (0.55) | FAAHCES1FAAH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152082-A1 | TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2010-02-17 | — | — | EP | claimed |
| WO-2008147553-A1 | TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-04 | — | — | WO | claimed |
| EP-2152082-A1 | TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008147553-A1 | TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-04 | — | — | WO | disclosed |