Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735618 | 0.85 | HPGD (0.32) | TSHRHPGDATM | |
| SCHEMBL16329381 | 0.76 | LPAR3 (0.39) | TSHRHPGD | |
| SCHEMBL27735547 | 0.75 | TSHR (0.36) | TSHRHPGDATMCYP3A4ALDH1A1 | |
| SCHEMBL10869033 | 0.74 | ATM (0.37) | TSHRHPGDATMCYP3A4ALDH1A1 | |
| SCHEMBL6822786 | 0.74 | ATM (0.37) | TSHRHPGDATMCYP3A4ALDH1A1 | |
| SCHEMBL29211176 | 0.72 | ATM (0.38) | TSHRHPGDATMCYP3A4ALDH1A1 | |
| SCHEMBL126725 | 0.72 | ADRB2 (0.36) | TSHRHPGDCYP3A4ALDH1A1ADRB2 | |
| SCHEMBL27996797 | 0.72 | TSHR (0.37) | TSHRHPGDCYP3A4ALDH1A1ADRB2 | |
| SCHEMBL6511720 | 0.70 | ATM (0.37) | TSHRHPGDATMCYP3A4ALDH1A1 | |
| SCHEMBL27735742 | 0.69 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |