Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748147 | 0.76 | CYP11B1 (0.53) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL19541946 | 0.76 | CYP11B1 (0.51) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL10770126 | 0.74 | TBXAS1 (0.43) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11228752 | 0.71 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11957613 | 0.71 | CYP19A1 (0.60) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL27756491 | 0.71 | MAPK8 (0.48) | CA5ACYP3A4MAPT | |
| SCHEMBL27722171 | 0.71 | MAPK8 (0.48) | CA5AMAPT | |
| SCHEMBL7573772 | 0.70 | TBXAS1 (0.46) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL25322490 | 0.70 | MAPK8 (0.47) | CA5ACYP3A4MAPT | |
| SCHEMBL30499962 | 0.70 | MAPK8 (0.47) | CA5ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410389-A | Organic compounds | NOVARTIS AG (CH) | 2009-04-15 | — | — | CN | disclosed |