Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406865 | 0.90 | KDM4E (0.47) | SMN1; SMN2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL406864 | 0.90 | KDM4E (0.47) | SMN1; SMN2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL8401255 | 0.90 | KDM4E (0.47) | SMN1; SMN2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL2773888 | 0.84 | MRGPRX4 (0.43) | SMN1; SMN2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL409948 | 0.84 | MEN1 (0.50) | SMN1; SMN2GAAMAP2K1CYP11B1CYP11B2 | |
| SCHEMBL536199 | 0.82 | MEN1 (0.46) | SMN1; SMN2GAATRPA1MAP2K1CYP11B1 | |
| SCHEMBL9968898 | 0.79 | KDM4E (0.51) | SMN1; SMN2GAAALDH1A1MAPTKMT2A | |
| SCHEMBL2776989 | 0.79 | KDM4E (0.51) | SMN1; SMN2GAAALDH1A1MAPTKMT2A | |
| SCHEMBL9968900 | 0.79 | RECQL (0.45) | SMN1; SMN2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL2776991 | 0.79 | KDM4E (0.51) | SMN1; SMN2GAAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193125-A2 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009043889-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2009-04-09 | — | — | WO | disclosed |