Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 18/20 | 0.52 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206006 | 0.81 | HSD11B1 (0.64) | HSD11B1 | |
| SCHEMBL3217876 | 0.74 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL3209355 | 0.68 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL3222984 | 0.68 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL3221302 | 0.68 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL3207656 | 0.67 | HSD11B1 (0.68) | HSD11B1F13A1TGM2TGM1 | |
| SCHEMBL3212631 | 0.66 | HSD11B1 (0.77) | HSD11B1 | |
| SCHEMBL27646777 | 0.66 | UTS2R (0.49) | — | |
| SCHEMBL3218473 | 0.65 | HSD11B1 (0.68) | HSD11B1 | |
| SCHEMBL3210352 | 0.65 | HSD11B1 (0.47) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400653-A | 11-beta HSD1 inhibitors | WYETH CORP (US) | 2009-04-01 | — | — | CN | disclosed |