Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 11/20 | 0.73 |
| ▸ | CPT1B | Q92523 | 9/20 | 0.73 |
| ▸ | CPT2 | P23786 | 7/20 | 0.73 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577725 | 0.91 | CPT1A (0.75) | CPT1ACPT1BCPT2PPARGPPARD | |
| SCHEMBL27715639 | 0.86 | CPT1A (0.72) | CPT1ACPT1BCPT2PPARGPPARD | |
| SCHEMBL3572875 | 0.84 | CPT1A (1.00) | CPT1ACPT1BCPT2PPARGPPARD | |
| SCHEMBL2906020 | 0.84 | CPT1A (0.77) | CPT1ACPT1BCPT2PPARGPPARD | |
| SCHEMBL27877814 | 0.82 | CPT1A (0.71) | CPT1ACPT1BCPT2PPARGPPARD | |
| SCHEMBL2898335 | 0.80 | CPT1A (1.00) | CPT1ACPT1BCPT2PPARGPPARD | |
| SCHEMBL3568174 | 0.77 | CPT1A (0.75) | CPT1ACPT1BCPT2PPARGPPARD | |
| SCHEMBL27736550 | 0.76 | CPT1A (0.56) | CPT1ACPT1BCPT2PPARGPPARD | |
| SCHEMBL27751900 | 0.76 | CPT1A (0.75) | CPT1ACPT1BCPT2PPARG | |
| SCHEMBL3576367 | 0.72 | CPT1A (0.76) | CPT1ACPT1BCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101263116-B | Novel heterobicyclic derivatives useful as liver carnitine palmitoyl transferase inhibitors | HOFFMAN-LA ROCHE LTD. (CH) | 2011-12-07 | — | — | CN | disclosed |
| CN-101263116-A | Novel heterobicyclic derivatives useful as liver carnitine palmitoyl transferase inhibitors | HOFFMANN LA ROCHE (CH) | 2008-09-10 | — | — | CN | disclosed |