Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757498 | 1.00 | HTR2C (0.51) | HTR2CTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL4674934 | 0.93 | HTR2C (0.52) | HTR2CPREPFKBP1ANPSR1 | |
| SCHEMBL6501753 | 0.89 | HTR2C (0.52) | HTR2CTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL6487292 | 0.89 | HTR2C (0.52) | HTR2CTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL3017853 | 0.89 | HTR2C (0.52) | HTR2CTSHRL3MBTL1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7013165 | 0.88 | HTR2C (0.51) | HTR2CTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL8220722 | 0.87 | HTR2C (0.53) | HTR2CTSHRL3MBTL1PREPNPSR1 | |
| SCHEMBL7251746 | 0.87 | HTR2C (0.53) | HTR2CTSHRL3MBTL1PREPNPSR1 | |
| SCHEMBL3788946 | 0.86 | HTR2C (0.49) | HTR2CTSHRL3MBTL1PREPFKBP1A | |
| SCHEMBL12479521 | 0.84 | SMN1; SMN2 (0.53) | HTR2CTSHRL3MBTL1PREPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101365693-A | Selected CGRP antagonists, method for the production thereof and use thereof as medicaments | BOEHRINGER INGELHEIM INT (DE) | 2009-02-11 | — | — | CN | disclosed |