Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.67 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729948 | 1.00 | MAP3K14 (0.67) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| Hydrochloric Acid SCHEMBL4654876 | 0.98 | MAP3K14 (0.65) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL3559500 | 0.80 | MAP3K14 (1.00) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL19829902 | 0.79 | MAP3K14 (0.45) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL1266237 | 0.79 | MAP3K14 (0.45) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL30216657 | 0.79 | MAP3K14 (0.45) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL31300318 | 0.79 | MAP3K14 (0.45) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL26962672 | 0.79 | MAP3K14 (0.45) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL3561436 | 0.79 | MAP3K14 (0.67) | MAP3K14ITGB2ICAM1ITGALLMNA | |
| SCHEMBL9786910 | 0.78 | MAP3K14 (0.49) | MAP3K14ITGB2ICAM1ITGALSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410396-A | Chromane derivatives | RAQUALIA PHARMA INC (JP) | 2009-04-15 | — | — | CN | disclosed |