Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17001810 | 0.80 | HTR1D (0.41) | — | |
| SCHEMBL15874354 | 0.75 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL5302092 | 0.71 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL15724298 | 0.71 | NPC1 (0.40) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL7600531 | 0.71 | CCNE1 (0.41) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL15804625 | 0.71 | KDM4E (0.38) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL11127892 | 0.69 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL728552 | 0.69 | NPC1 (0.42) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL16216909 | 0.67 | BACE1 (0.34) | HRH4 | |
| SCHEMBL14555680 | 0.67 | TLR8 (0.38) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103874697-A | Dibenzooxepin derivative | KYOWA HAKKO KIRIN CO LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-101410114-B | A3 adenosine receptor allosteric modulators | US GOV HEALTH & HUMAN SERV (US) | 2012-07-04 | — | — | CN | disclosed |
| CN-101410114-A | A3 adenosine receptor allosteric modulators | US GOV HEALTH & HUMAN SERV (US) | 2009-04-15 | — | — | CN | disclosed |