Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL21145308 | 0.87 | FFAR3 (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Valeric Acid SCHEMBL21145150 | 0.83 | AKR1B1 (0.58) | LMNACYP1A2FFAR3HDAC3HDAC1 | |
| Glycolic Acid SCHEMBL21145059 | 0.82 | FFAR3 (0.35) | LMNAGABRPGABRDGABRA1GABRB1 | |
| Propionic Acid SCHEMBL21145096 | 0.82 | FFAR3 (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hexanoate SCHEMBL21145336 | 0.81 | AKR1B1 (0.70) | LMNACYP1A2OR51E2SLC22A6APEX1 | |
| Succinic Acid SCHEMBL8397315 | 0.81 | EGLN1 (0.69) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL5874469 | 0.80 | EGLN1 (0.50) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL21081056 | 0.78 | LMNA (0.64) | EGLN1LMNAALKBH5SUCNR1SLC15A2 | |
| Oxalic Acid SCHEMBL21145175 | 0.78 | TP53 (0.39) | FFAR3 | |
| Acetic Acid SCHEMBL21145178 | 0.78 | FFAR3 (0.50) | LMNAFFAR3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101264414-B | Green high-efficiency recyclable SO2 gas absorbent and preparation thereof | UNIV HEFEI TECHNOLOGY | 2010-10-06 | — | — | CN | disclosed |
| CN-101264414-A | Green high-efficiency recyclable SO2 gas absorbent and preparation thereof | UNIV HEFEI TECHNOLOGY (CN) | 2008-09-17 | — | — | CN | disclosed |