Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.66 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180670 | 0.83 | DGAT1 (0.63) | DGAT1SOAT1 | |
| SCHEMBL180837 | 0.83 | DGAT1 (0.70) | DGAT1SOAT1 | |
| SCHEMBL180706 | 0.82 | DGAT1 (0.57) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL180890 | 0.82 | DGAT1 (0.64) | DGAT1SOAT1 | |
| SCHEMBL180715 | 0.81 | DGAT1 (0.66) | DGAT1SOAT1 | |
| SCHEMBL180461 | 0.81 | DGAT1 (0.65) | DGAT1SOAT1 | |
| SCHEMBL180803 | 0.81 | DGAT1 (0.61) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL4237043 | 0.80 | DGAT1 (0.71) | DGAT1 | |
| SCHEMBL180608 | 0.80 | DGAT1 (1.00) | DGAT1SOAT1 | |
| SCHEMBL180692 | 0.80 | DGAT1 (0.71) | DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086981-A | New compounds | NOVARTIS AG | 2013-05-08 | — | — | CN | claimed |
| CN-101415683-A | Novel compounds | NOVARTIS AG (CH) | 2009-04-22 | — | — | CN | claimed |
| CN-103288721-A | (4-(4-[6-(trifluoromethyl-pyridin-3-ylamino)-n-containing-heteroaryl]-phenyl)-cyclohexyl)-acetic acid derivatives and pharmaceutical uses thereof | NOVARTIS AG | 2013-09-11 | — | — | CN | disclosed |
| CN-101415683-B | Novel compounds | NOVARTIS AG | 2013-07-17 | — | — | CN | disclosed |
| CN-103086981-A | New compounds | NOVARTIS AG | 2013-05-08 | — | — | CN | disclosed |
| CN-101600437-A | method for preventing or treating myocardial ischemia | NOVARTIS AG (CH) | 2009-12-09 | — | — | CN | disclosed |
| CN-101415683-A | Novel compounds | NOVARTIS AG (CH) | 2009-04-22 | — | — | CN | disclosed |