Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109327 | 0.83 | MAPT (0.46) | MAPTTSHRALDH1A1RECQLHTT | |
| SCHEMBL3924109 | 0.75 | MAPT (0.54) | MAPTTSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL2038302 | 0.74 | MAPT (0.73) | MAPTTSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL2056734 | 0.73 | TSHR (0.55) | MAPTTSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL14174537 | 0.73 | ALDH1A1 (0.62) | MAPTTSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL8893806 | 0.72 | ALDH1A1 (0.45) | MAPTTSHRALDH1A1RECQLHTT | |
| SCHEMBL4592723 | 0.71 | ALDH1A1 (0.35) | TSHRALDH1A1CYP3A4RECQLKDM4E | |
| SCHEMBL8632555 | 0.71 | ALDH1A1 (0.41) | MAPTTSHRALDH1A1HTTKDM4E | |
| SCHEMBL11765935 | 0.71 | TSHR (0.57) | MAPTTSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL11765920 | 0.71 | TSHR (0.57) | MAPTTSHRALDH1A1CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384303-A | Coloring agent for coloring keratin fibers | WELLA AG (US) | 2009-03-11 | — | — | CN | disclosed |
| CN-101374495-A | Colorant for keratin fibers | PROCTER & GAMBLE (US) | 2009-02-25 | — | — | CN | disclosed |