Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28799709 | 0.84 | CXCR2 (0.47) | KCNMA1SMN1; SMN2TSHRHSD17B10CXCR2 | |
| SCHEMBL3908318 | 0.84 | CXCR2 (0.47) | KCNMA1SMN1; SMN2TSHRHSD17B10CXCR2 | |
| SCHEMBL1624694 | 0.83 | TSHR (0.45) | KCNMA1SMN1; SMN2TSHRHSD17B10CXCR2 | |
| SCHEMBL11900645 | 0.81 | CXCR2 (0.58) | KCNMA1SMN1; SMN2TSHRHSD17B10CXCR2 | |
| SCHEMBL3911920 | 0.80 | TSHR (0.49) | KCNMA1SMN1; SMN2TSHRHSD17B10CXCR2 | |
| SCHEMBL31047229 | 0.80 | TSHR (0.49) | KCNMA1SMN1; SMN2TSHRHSD17B10CXCR2 | |
| SCHEMBL2772541 | 0.78 | ALDH1A1 (0.67) | SMN1; SMN2TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL2773784 | 0.77 | MEN1 (0.49) | KCNMA1SMN1; SMN2TSHRCXCR2TDP1 | |
| SCHEMBL7499979 | 0.75 | MAPT (0.55) | SMN1; SMN2TSHRHSD17B10CXCR2TDP1 | |
| SCHEMBL3045742 | 0.75 | TSHR (0.56) | KCNMA1SMN1; SMN2TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220062-A1 | NEW HUMAN PAPILLOMA VIRUS INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Anaconda Pharma (FR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009065893-A1 | NEW HUMAN PAPILLOMA VIRUS INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ANACONDA PHARMA (FR) | 2009-05-28 | — | — | WO | disclosed |