Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 11/20 | 0.51 |
| ▸ | METAP1 | P53582 | 6/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | CAD | P27708 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27182944 | 1.00 | METAP2 (0.51) | METAP2METAP1S1PR1S1PR3DPP4 | |
| SCHEMBL10346849 | 0.87 | S1PR1 (0.41) | METAP2METAP1S1PR1S1PR3DPP4 | |
| SCHEMBL10748731 | 0.86 | BIRC2 (0.42) | METAP2METAP1S1PR1S1PR3DPP4 | |
| SCHEMBL27524339 | 0.86 | BIRC2 (0.42) | METAP2METAP1S1PR1S1PR3DPP4 | |
| SCHEMBL10700935 | 0.86 | BIRC2 (0.42) | METAP2METAP1S1PR1S1PR3DPP4 | |
| Hydrochloric Acid SCHEMBL23404051 | 0.85 | BIRC2 (0.41) | METAP2METAP1S1PR1S1PR3DPP4 | |
| SCHEMBL8644895 | 0.85 | METAP2 (0.55) | METAP2METAP1 | |
| SCHEMBL8644894 | 0.85 | METAP2 (0.55) | METAP2METAP1 | |
| SCHEMBL27183387 | 0.84 | S1PR1 (0.48) | METAP2METAP1S1PR1S1PR3DPP4 | |
| SCHEMBL10346838 | 0.83 | DPP4 (0.37) | METAP2METAP1S1PR1S1PR3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429533-A | Synthesis process with amide zymoid method for pressure reduction azeotropy continuous water elimination | UNIV JIANGNAN (CN) | 2009-05-13 | — | — | CN | disclosed |
| CN-101418323-A | A kind of azeotropic water removing coupling simulated moving bed amides enzyme method production process | UNIV JIANGNAN (CN) | 2009-04-29 | — | — | CN | disclosed |