Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 9/20 | 0.46 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776611 | 1.00 | CRBN (0.47) | CRBNDDB1KCNA5PDCD1LG2CD274 | |
| SCHEMBL1777915 | 0.84 | ALDH1A1 (0.40) | CRBNDDB1PDCD1LG2CD274IRAK4 | |
| SCHEMBL1776281 | 0.84 | CD274 (0.40) | KCNA5PDCD1LG2CD274TACR1IRAK4 | |
| SCHEMBL1776113 | 0.84 | DDB1 (0.44) | CRBNDDB1KCNA5PDCD1LG2CD274 | |
| SCHEMBL1775634 | 0.84 | CRBN (0.42) | CRBNDDB1KCNA5PDCD1LG2CD274 | |
| SCHEMBL1776665 | 0.84 | TACR1 (0.45) | CRBNDDB1PDCD1LG2CD274TACR1 | |
| SCHEMBL1777213 | 0.82 | KCNA5 (0.46) | KCNA5PDCD1LG2CD274KDM4EPOLB | |
| SCHEMBL1776764 | 0.81 | CNR1 (0.41) | CRBNDDB1KCNA5PDCD1LG2CD274 | |
| SCHEMBL1776816 | 0.79 | CD274 (0.53) | KCNA5PDCD1LG2CD274 | |
| SCHEMBL1776409 | 0.77 | DDB1 (0.46) | CRBNDDB1KCNA5PDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296902-A | Compounds comprising lactam or lactam derivative moieties, processes for preparing them and their use | UCB PHARMA SA (BE) | 2008-10-29 | — | — | CN | claimed |
| CN-101296902-A | Compounds comprising lactam or lactam derivative moieties, processes for preparing them and their use | UCB PHARMA SA (BE) | 2008-10-29 | — | — | CN | disclosed |