Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828937 | 0.98 | NAAA (0.59) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL7287260 | 0.95 | NAAA (0.63) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL15619801 | 0.93 | NAAA (0.66) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL18941412 | 0.92 | NAAA (0.64) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL27538955 | 0.91 | NAAA (0.49) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL2048685 | 0.89 | NAAA (0.54) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL4570309 | 0.85 | NAAA (0.72) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL17675641 | 0.85 | NAAA (0.79) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL207867 | 0.85 | NAAA (0.79) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 | |
| SCHEMBL19150279 | 0.85 | NAAA (0.72) | NAAACYP2C19SMN1; SMN2HTTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116018334-A | Process for preparing 3- (cyclohex-1-en-1-yl) propanal derivatives | 弗门尼舍有限公司 | 2023-04-25 | — | — | CN | claimed |
| CN-116018334-A | Process for preparing 3- (cyclohex-1-en-1-yl) propanal derivatives | 弗门尼舍有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-101668423-B | 2-aminopyrimidine modulators of the histamine H4 receptor | JANSSEN PHARMACEUTICA NV | 2013-10-30 | — | — | CN | disclosed |
| CN-101668423-A | 2-aminopyrimidine modulators of the histamine h4 receptor | JANSSEN PHARMACEUTICA NV | 2010-03-10 | — | — | CN | disclosed |
| CN-101410387-A | Pyridyl-and pyrimidinyl-substituted pyrrole-, thiophene-and furan-derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL (IT) | 2009-04-15 | — | — | CN | disclosed |