Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 10/20 | 0.62 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775682 | 0.91 | CDC7 (0.64) | CDC7JAK2IKBKBCCNT1CCNB2 | |
| SCHEMBL27759244 | 0.91 | CDC7 (0.52) | CDC7JAK2IKBKBCCNT1CCNB2 | |
| SCHEMBL3603923 | 0.84 | CDC7 (0.65) | CDC7JAK2IKBKBCCNT1CCNB2 | |
| SCHEMBL28779560 | 0.82 | CDC7 (0.80) | CDC7JAK2IKBKBCCNT1CCNB2 | |
| SCHEMBL27759272 | 0.80 | CDC7 (0.70) | CDC7JAK2IKBKBCCNT1CCNB2 | |
| SCHEMBL4183402 | 0.78 | CDC7 (0.66) | CDC7JAK2IKBKBCCNT1CCNB2 | |
| SCHEMBL4182044 | 0.77 | CDC7 (1.00) | CDC7JAK2IKBKBCCNT1CCNB2 | |
| SCHEMBL4187750 | 0.74 | CDC7 (0.65) | CDC7JAK2IKBKBCCNT1CCNB2 | |
| SCHEMBL3596692 | 0.73 | CDC7 (0.52) | CDC7NPC1RAB9AKDM4E | |
| SCHEMBL27759394 | 0.72 | CDC7 (0.64) | CDC7JAK2IKBKBCCNT1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101410387-A | Pyridyl-and pyrimidinyl-substituted pyrrole-, thiophene-and furan-derivatives as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL (IT) | 2009-04-15 | — | — | CN | disclosed |