Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 8/20 | 0.65 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | CLK1 | P49759 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183402 | 0.89 | CDC7 (0.66) | CDC7IKBKBCCNT1JAK2CCNB2 | |
| SCHEMBL4187750 | 0.88 | CDC7 (0.65) | CDC7IKBKBCCNT1JAK2CCNB2 | |
| SCHEMBL3596692 | 0.84 | CDC7 (0.52) | CDC7KMT2A | |
| SCHEMBL27738533 | 0.84 | CDC7 (0.62) | CDC7IKBKBCCNT1JAK2CCNB2 | |
| SCHEMBL4182044 | 0.79 | CDC7 (1.00) | CDC7IKBKBCCNT1JAK2CCNB2 | |
| SCHEMBL28775682 | 0.78 | CDC7 (0.64) | CDC7IKBKBCCNT1JAK2CCNB2 | |
| SCHEMBL4190784 | 0.77 | CDC7 (1.00) | CDC7IKBKBCCNT1JAK2CCNB2 | |
| SCHEMBL28779560 | 0.75 | CDC7 (0.80) | CDC7IKBKBCCNT1JAK2CCNB2 | |
| SCHEMBL13977106 | 0.74 | CDC7 (0.62) | CDC7IKBKBCCNT1JAK2CCNB2 | |
| SCHEMBL15300434 | 0.74 | CDC7 (0.71) | CDC7IKBKBCCNT1JAK2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109702-A1 | NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF | GENOSCO INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-20250276972-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) | 2025-09-04 | — | — | US | disclosed |
| EP-4247790-B1 | STING ANTAGONISTS AND USES THEREOF | REGOR PHARMACEUTICALS INC (US) | 2024-10-09 | — | — | EP | disclosed |
| WO-2024148210-A1 | CYCLIN-DEPENDENT KINASE 12 MODULATORS AND THERAPEUTIC USES THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | WO | disclosed |
| US-20240051956-A1 | SOS1 INHIBITORS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2024-02-15 | — | — | US | disclosed |
| US-20240002368-A1 | STING ANTAGONISTS AND USES THEREOF | REGOR PHARMACEUTICALS, INC. | 2024-01-04 | — | — | US | disclosed |
| EP-4267250-A1 | SOS1 INHIBITORS AND USES THEREOF | Qilu Regor Therapeutics Inc. (CN) | 2023-11-01 | — | — | EP | disclosed |
| WO-2023195530-A1 | URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 | 2023-10-12 | — | — | WO | disclosed |
| WO-2023195529-A1 | URACIL DERIVATIVE HAVING VIRAL GROWTH INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 | 2023-10-12 | — | — | WO | disclosed |
| WO-2022140427-A1 | SOS1 INHIBITORS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-06-30 | — | — | WO | disclosed |
| US-20090099221-A1 | PYRIDYL-AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE-AND FURANE-DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-04-16 | — | — | US | disclosed |
| EP-2004623-A1 | PYRIDYL- AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE- AND FURANE-DERIVATIVES AS KINASE INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008065054-A1 | TRICYCLIC INDOLES AND (4,5-DIHYDRO) INDOLES | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2008-06-05 | — | — | WO | disclosed |
| EP-1756086-B1 | PYRIDIN-4-YL-ETHYNYL-IMIDAZOLES AND PYRAZOLES AS MGLU5 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007110344-A1 | PYRIDYL- AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE- AND FURANE-DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-10-04 | — | — | WO | disclosed |
| EP-1756086-A1 | PYRIDIN-4-YL-ETHYNYL-IMIDAZOLES AND PYRAZOLES AS MGLU5 RECEPTOR ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-02-28 | — | — | EP | disclosed |
| US-7183435-B2 | Hexasubstituted with a tertiary amino phenyl groups; stability, rapid response and good transportability; electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20060030559-A1 | Diazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2006-02-09 | — | — | US | disclosed |
| US-20060024595-A1 | Triphenylene compound, method for making | RICOH COMPANY, LTD. (JP) | 2006-02-02 | — | — | US | disclosed |
| WO-2005118568-A1 | PYRIDIN-4-YL-ETHYNYL-IMIDAZOLES AND PYRAZOLES AS MGLU5 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060024595-A1 | Triphenylene compound, method for making | ALDH1A2, PDE6C, NR2E3 | CDC7 2884/4885IKBKB 4306/4885CCNT1 1858/4885 |
| US-20090099221-A1 | PYRIDYL-AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE-AND FURANE-DERIVATIVES AS KINASE INHIBITORS | CDK2, CDK1, CDK5 | CDC7 294/4885IKBKB 684/4885CCNT1 84/4885 |
| US-20060030559-A1 | Diazole derivatives | GRM1, GRM2, GRIN2B | CDC7 4692/4885IKBKB 3956/4885CCNT1 1773/4885 |
| US-20260109702-A1 | NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF | CRBN, PSMB3, PSMB1 | CDC7 872/4885IKBKB 1144/4885CCNT1 452/4885 |
| US-20240002368-A1 | STING ANTAGONISTS AND USES THEREOF | STING1, TBK1, CGAS | CDC7 2403/4885IKBKB 105/4885CCNT1 4869/4885 |
| US-20250276972-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | PACSIN2, CSNK1A1, CSNK1G3 | CDC7 229/4885IKBKB 246/4885CCNT1 705/4885 |
| US-20240051956-A1 | SOS1 INHIBITORS AND USES THEREOF | SOS1, KRAS, NRAS | CDC7 1754/4885IKBKB 497/4885CCNT1 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.