SCHEMBL2773876

SCHEMBL2773876

C=Cc1ccc(CC(CC(F)(F)F)OC(Cc2ccc(C=C)cc2)CC(F)(F)F)cc1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2771988 0.86 ALDH1A1 (0.31) ALDH1A1
SCHEMBL8196547 0.85 ALDH1A1 (0.35) ALDH1A1
SCHEMBL7783040 0.85 ALDH1A1 (0.31) ALDH1A1
SCHEMBL3474952 0.77 ALDH1A1 (0.41) ALDH1A1
SCHEMBL2772308 0.76 ALDH1A1 (0.39) ALDH1A1
SCHEMBL2771085 0.74
SCHEMBL7787968 0.73 ALDH1A1 (0.37) ALDH1A1
SCHEMBL2275914 0.73 ALDH1A1 (0.37) ALDH1A1
SCHEMBL4248554 0.72 ALDH1A1 (0.35) ALDH1A1
SCHEMBL10700065 0.71 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2174966-A1 OPTICAL MATERIAL AND OPHTHALMIC LENS MADE OF THE SAME Menicon Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-0890636-B1 Culture vessel MENICON CO LTD (JP) 2001-10-31 EP disclosed
US-6018001-A ACID TREATMENT OF A CONTACT LENS WHICH IS A COPOLYMER OF ASUGAR KETAL-CONTAINING (METH)ACRYLATE AND A SUGAR GLYCEROL KETAL-CONTAINING (METH)ACRYLATE AND A CO-MONOMER CONTAINING SILICON AND FLUORINE-MONOMER; OXYGEN PERMEABILITY MENICON CO., LTD. (JP) 2000-01-25 US disclosed
EP-0488145-B1 Ultraviolet light absorbing intraocular lens MENICON CO LTD (JP) 1999-06-09 EP disclosed
EP-0892297-A1 PROCESS FOR PRODUCING CONTACT LENS WITH HYDROPHILIC SURFACE AND CONTACT LENS OBTAINED THEREBY MENICON CO., LTD. (JP) 1999-01-20 EP disclosed
EP-0890636-A1 Culture vessel Menicon Co., Ltd. (JP) 1999-01-13 EP disclosed
US-5147902-A Benzotriazole compound MENICON CO., LTD. (JP) 1992-09-15 US disclosed
EP-0488145-A2 Ultraviolet light absorbing ocular lens Menicon Co., Ltd. (JP) 1992-06-03 EP disclosed