Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804909 | 0.89 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27834736 | 0.89 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL41918 | 0.88 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Sulfuric Acid SCHEMBL27788501 | 0.87 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Iodide SCHEMBL27806997 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL600420 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| Bromide SCHEMBL28205864 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27842116 | 0.85 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| Chloromethane SCHEMBL27319912 | 0.84 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| Trifluoromethanesulfonic Acid SCHEMBL27972974 | 0.84 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101371955-B | Process for dewatering a mineral slurry concentrate and increasing the production of a filter cake | NEO SOLUTIONS INC | 2013-02-20 | — | — | CN | claimed |
| CN-101371955-A | Process for dewatering a mineral slurry concentrate and increasing the production of a filter cake | NEO SOLUTIONS INC (US) | 2009-02-25 | — | — | CN | claimed |
| CN-101371955-B | Process for dewatering a mineral slurry concentrate and increasing the production of a filter cake | NEO SOLUTIONS INC | 2013-02-20 | — | — | CN | disclosed |
| CN-101371955-A | Process for dewatering a mineral slurry concentrate and increasing the production of a filter cake | NEO SOLUTIONS INC (US) | 2009-02-25 | — | — | CN | disclosed |