Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41918 | 0.98 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Bromide SCHEMBL28205864 | 0.96 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| Iodide SCHEMBL27806997 | 0.96 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| Chloromethane SCHEMBL27319912 | 0.94 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| Sulfuric Acid SCHEMBL27788501 | 0.89 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylic Acid SCHEMBL3223311 | 0.88 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| Acrylamide SCHEMBL27797437 | 0.88 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27738784 | 0.86 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27834736 | 0.85 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL15155490 | 0.85 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12553188-B2 | GPAM compositions and methods | KEMIRA OYJ (FI) | 2026-02-17 | — | — | US | claimed |
| EP-4667550-A1 | DEGRADABLE NANOMATERIAL AND PREPARATION METHOD THEREFOR AND USE THEREOF, AND FRACTURING FLUID | China Petroleum & Chemical Corporation (CN) | 2025-12-24 | — | — | EP | claimed |
| EP-4623154-A1 | WATER SOLUBLE AMPHOTERIC EMULSION TERPOLYMERS, METHODS OF MAKING, AND METHODS OF USE AS RETENTION AND DEWATERING AIDS | KEMIRA OYJ (FI) | 2025-10-01 | — | — | EP | claimed |
| EP-4612484-A1 | REAL TIME MONITORING OF POLYMER MIXTURES USING REFRACTOMETRY | KEMIRA OYJ (FI) | 2025-09-10 | — | — | EP | claimed |
| CN-119524814-A | Dual-functional composite material and preparation method and application thereof | 河海大学 | 2025-02-28 | — | — | CN | claimed |
| EP-4476183-A2 | METHOD OF DEWATERING SLUDGE | Solenis Technologies Cayman, L.P. (CH) | 2024-12-18 | — | — | EP | claimed |
| CN-113926427-B | Modified graphene film for capturing carbon dioxide in air and preparation method thereof | 济南产研国能中碳环保技术有限公司 | 2024-07-19 | — | — | CN | claimed |
| WO-2024145469-A1 | WATER SOLUBLE AMPHOTERIC EMULSION TERPOLYMERS, METHODS OF MAKING, AND METHODS OF USE AS RETENTION AND DEWATERING AIDS | KEMIRA OYJ (FI) | 2024-07-04 | — | — | WO | claimed |
| WO-2024119022-A1 | REAL TIME MONITORING OF POLYMER MIXTURES USING REFRACTOMETRY | KEMIRA OYJ (FI) | 2024-06-06 | — | — | WO | claimed |
| CN-117363212-B | Organic silicon marine antifouling paint based on affinity synergistic effect | 常熟理工学院 | 2024-05-17 | — | — | CN | claimed |
| WO-2014193756-A1 | AMPHOLYTE POLYMERIC COMPOUNDS IN SUBTERRANEAN APPLICATIONS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-12-04 | — | — | WO | claimed |
| WO-2014193834-A1 | AMPHOLYTE POLYMERIC COMPOUNDS IN SUBTERRANEAN APPLICATIONS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-12-04 | — | — | WO | claimed |
| US-20140352960-A1 | Ampholyte Polymeric Compounds in Subterranean Applications | HALLIBURTON ENERGY SERVICES, INC. (US) | 2014-12-04 | — | — | US | claimed |
| CN-103509180-A | Polymer dispersion and process for preparing a polymer dispersion | AKZO NOBEL NV | 2014-01-15 | — | — | CN | claimed |
| WO-2013149714-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS COMPRISING A CORE AND A RANDOM - COPOLYMER COATING | MERCK PATENT GMBH (DE) | 2013-10-10 | — | — | WO | claimed |
| CN-101094881-A | Polymer dispersion and method for producing a polymer dispersion | AKZO NOBEL NV (NL) | 2007-12-26 | — | — | CN | claimed |
| EP-1761241-A1 | USE AS AN ANTIPERSPIRANT AGENT OF A FLOCCULATING WATER-SOLUBLE POLYMER; COSMETIC PROCESS FOR TREATING PERSPIRATION | l'Oreal SA (FR) | 2007-03-14 | — | — | EP | claimed |
| WO-2006050811-A1 | GRAFTS POLYMERS | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 2006-05-18 | — | — | WO | claimed |
| WO-2005120448-A1 | USE AS AN ANTIPERSPIRANT AGENT OF A FLOCCULATING WATER-SOLUBLE POLYMER; COSMETIC PROCESS FOR TREATING PERSPIRATION | L'OREAL (FR) | 2005-12-22 | — | — | WO | claimed |
| EP-0627327-B1 | Offset printing process and aqueous composition therefor | HOECHST FRANCE (FR) | 1996-10-23 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12553188-B2 | GPAM compositions and methods | PGM2, SLC6A9, GNMT | TSHR 4437/4885HPGD 1604/4885ALDH1A1 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.