Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | FABP7 | O15540 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031702 | 0.94 | KMT2A (0.51) | KMT2AFABP5FABP7CASP3CA1 | |
| SCHEMBL7853751 | 0.90 | KMT2A (0.55) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL29989813 | 0.90 | KMT2A (0.55) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL6136463 | 0.88 | KMT2A (0.56) | KMT2AFABP5FABP7CASP3CA1 | |
| SCHEMBL29670230 | 0.88 | KMT2A (0.56) | KMT2AFABP5FABP7CASP3CA1 | |
| SCHEMBL13329984 | 0.86 | KMT2A (0.58) | KMT2AFABP5FABP7CASP3CA1 | |
| SCHEMBL5148054 | 0.85 | KMT2A (0.60) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL15160787 | 0.84 | KMT2A (0.47) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL5031690 | 0.84 | KMT2A (0.53) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL31300437 | 0.83 | KMT2A (0.46) | KMT2AFABP5FABP7CASP3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421609-A | The method relevant, potpourri, kit and composition with analyte determination | APPLERA CORP (US) | 2009-04-29 | — | — | CN | disclosed |