SCHEMBL6136463

SCHEMBL6136463

CN(CCCC(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
FABP5 Q01469 3/20 0.44
FABP7 O15540 2/20 0.44
CASP3 P42574 2/20 0.41
EGFR P00533 1/20 0.40
EPHX2 P34913 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
FFAR4 Q5NUL3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670230 1.00 KMT2A (0.56) KMT2AFABP5FABP7CASP3EGFR
SCHEMBL13329984 0.96 KMT2A (0.58) KMT2AFABP5FABP7CASP3EGFR
SCHEMBL5148054 0.95 KMT2A (0.60) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL7853751 0.92 KMT2A (0.55) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL29989813 0.92 KMT2A (0.55) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL12703322 0.90 KMT2A (0.44) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL12703276 0.89 KMT2A (0.46) KMT2AFABP5FABP7CASP3EPHX2
Succinic Acid SCHEMBL27739367 0.88 KMT2A (0.48) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL14656652 0.87 KMT2A (0.47) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL23156989 0.86 KMT2A (0.42) KMT2AFABP5FABP7CASP3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3939959-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND Nissan Chemical Corporation (JP) 2022-01-19 EP disclosed
US-20210061860-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-03-04 US disclosed
US-20200131669-A1 CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2020-04-30 US disclosed
US-9409952-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-08-09 US disclosed
US-9409952-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-08-09 US disclosed
EP-2813512-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD Chugai Seiyaku Kabushiki Kaisha (JP) 2014-12-17 EP disclosed
US-8889843-B2 Nucleic acid synthesizing dimer amidite and nucleic acid synthesizing method APTA BIOSCIENCES LTD. (GB) 2014-11-18 US disclosed
US-8889843-B2 Nucleic acid synthesizing dimer amidite and nucleic acid synthesizing method APTA BIOSCIENCES LTD. (GB) 2014-11-18 US disclosed
WO-2013100132-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD 中外製薬株式会社 (JP) 2013-07-04 WO disclosed
US-8299225-B2 Amidite for synthesizing modified nucleic acid and method for synthesizing modified nucleic acid FUJITSU LIMITED (JP) 2012-10-30 US disclosed
US-7910726-B2 Amidite for synthesizing modified nucleic acid and method for synthesizing modified nucleic acid FUJITSU LIMITED (JP) 2011-03-22 US disclosed
US-7910726-B2 Amidite for synthesizing modified nucleic acid and method for synthesizing modified nucleic acid FUJITSU LIMITED (JP) 2011-03-22 US disclosed
US-20100197902-A1 NUCLEIC ACID SYNTHESIZING DIMER AMIDITE AND NUCLEIC ACID SYNTHESIZING METHOD FUJITSU LIMITED (JP) 2010-08-05 US disclosed
US-20100197902-A1 NUCLEIC ACID SYNTHESIZING DIMER AMIDITE AND NUCLEIC ACID SYNTHESIZING METHOD FUJITSU LIMITED (JP) 2010-08-05 US disclosed
US-20090062521-A1 AMIDITE FOR SYNTHESIZING MODIFIED NUCLEIC ACID AND METHOD FOR SYNTHESIZING MODIFIED NUCLEIC ACID FUJITSU LIMITED (JP) 2009-03-05 US disclosed
US-20090062521-A1 AMIDITE FOR SYNTHESIZING MODIFIED NUCLEIC ACID AND METHOD FOR SYNTHESIZING MODIFIED NUCLEIC ACID FUJITSU LIMITED (JP) 2009-03-05 US disclosed
EP-1042279-B1 SUBSTITUTED BETA-ALANINES AVENTIS PHARMA LTD (GB) 2005-03-02 EP disclosed
US-6352977-B1 ALANINE WITH PRODRUGS AVENTIS PHARMA LIMITED (GB) 2002-03-05 US disclosed
EP-1042279-A1 SUBSTITUTED BETA-ALANINES Aventis Pharma Limited (GB) 2000-10-11 EP disclosed
WO-1999033789-A1 SUBSTITUTED β-ALANINES AVENTIS PHARMA LIMITED (GB) 1999-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061860-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R KMT2A 4608/4885FABP5 2565/4885FABP7 3166/4885
US-20200131669-A1 CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME VIP, SLC7A1, TRPV1 KMT2A 4201/4885FABP5 1216/4885FABP7 712/4885
US-20090062521-A1 AMIDITE FOR SYNTHESIZING MODIFIED NUCLEIC ACID AND METHOD FOR SYNTHESIZING MODIFIED NUCLEIC ACID NSUN2, RNMT, ADAR KMT2A 595/4885FABP5 3103/4885FABP7 3083/4885
US-20100197902-A1 NUCLEIC ACID SYNTHESIZING DIMER AMIDITE AND NUCLEIC ACID SYNTHESIZING METHOD ADAR, RNGTT, ATIC KMT2A 2434/4885FABP5 2140/4885FABP7 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.