Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469145 | 0.85 | REN (0.35) | RENSLC6A4KCNH2SLC6A2SLC6A3 | |
| SCHEMBL27740106 | 0.84 | REN (0.43) | RENSLC6A4KCNH2GRM5HTR1A | |
| SCHEMBL13139892 | 0.84 | REN (0.43) | RENSLC6A4KCNH2GRM5HTR1A | |
| SCHEMBL3474804 | 0.83 | REN (0.34) | RENGRM5 | |
| SCHEMBL3076004 | 0.81 | REN (0.44) | REN | |
| SCHEMBL8284795 | 0.81 | REN (0.44) | REN | |
| SCHEMBL13030761 | 0.81 | REN (0.46) | REN | |
| SCHEMBL3066635 | 0.81 | REN (0.46) | REN | |
| SCHEMBL3079266 | 0.81 | REN (0.43) | REN | |
| SCHEMBL13030760 | 0.81 | REN (0.43) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101501020-A | Nitrate esters of piperidines | SPEEDEL EXPERIMENTA AG (CH) | 2009-08-05 | — | — | CN | disclosed |
| CN-101370806-A | Substituted 4-phenylpiperidines | SPEEDEL EXPERIMENTA AG (CH) | 2009-02-18 | — | — | CN | disclosed |