SCHEMBL2774046

SCHEMBL2774046

CN(CC(=O)OP)C(=N)N

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 19/20 0.40
CA2 P00918 19/20 0.40
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3812152 0.83 NOS3 (0.39) CA1CA2NOS3NOS1NOS2
SCHEMBL3056410 0.81 CA1 (0.41) CA1CA2NOS3NOS1NOS2
Water SCHEMBL21810558 0.81 NOS3 (0.38) CA1CA2NOS3NOS1NOS2
SCHEMBL19152428 0.81 CA1 (0.42) CA1CA2NOS3NOS1NOS2
SCHEMBL13897077 0.81 NOS3 (0.38) CA1CA2NOS3NOS1NOS2
SCHEMBL5326458 0.79 NOS3 (0.37) CA1CA2NOS3NOS1NOS2
SCHEMBL28254066 0.79 NOS3 (0.37) CA1CA2NOS3NOS1NOS2
Creatine SCHEMBL21567 0.78
Creatine SCHEMBL30063981 0.78
Creatine SCHEMBL27979093 0.78 NOS3 (0.46) CA1CA2NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106011163-A Method for cell-free expression of signal protein and expression system 武汉华美生物工程有限公司 2016-10-12 CN claimed
CN-110408635-A A kind of application of the nucleic acid constructs containing Streptavidin element in protein expression, purifying KANGMA SHANGHAI BIOTECHNOLOGY CO LTD 2019-11-05 CN disclosed
CN-108949801-B A method of by knocking out nucleic acid enzyme system to regulate and control external biological synthesizing activity 康码(上海)生物科技有限公司 2019-06-14 CN disclosed
CN-109837293-A A kind of series connection DNA element that can enhance protein synthesis efficiency 康码(上海)生物科技有限公司 2019-06-04 CN disclosed
CN-109154001-A Novel minimal UTR sequences 埃泽瑞斯公司 2019-01-04 CN disclosed
CN-103768037-B There is antitumor and reduction induced cardiotoxicity slow releasing pharmaceutical nanoparticle and preparation method thereof by carrier of amphiphilic compound 华南理工大学 2017-10-20 CN disclosed
CN-103098561-B The manufacture method of stiffener integral type flexible printing substrate and stiffener integral type flexible printing substrate KANEKA CORP. (JP) 2015-11-25 CN disclosed
US-20140350497-A1 DEVICE AND METHOD FOR TREATING CENTRAL NERVOUS SYSTEM PATHOLOGY WAKE FOREST UNIVERSITY HEALTH SCIENCES 2014-11-27 US disclosed
CN-103990184-A Device and method for treating central nervous system pathology WAKE FOREST UNIVERSITY HEATH SCIENCES 2014-08-20 CN disclosed
US-8764794-B2 Device and method for treating central nervous system pathology WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2014-07-01 US disclosed
US-20130072827-A1 DEVICE AND METHOD FOR TREATING CENTRAL NERVOUS SYSTEM PATHOLOGY WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2013-03-21 US disclosed
US-8267960-B2 Device and method for treating central nervous system pathology WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2012-09-18 US disclosed
CN-102014980-A Devices and methods for treating central nervous system pathologies UNIV WAKE FOREST HEALTH SCIENCES 2011-04-13 CN disclosed
EP-2237812-A1 DEVICE AND METHOD FOR TREATING CENTRAL NERVOUS SYSTEM PATHOLOGY Wake Forest University Health Sciences (US) 2010-10-13 EP disclosed
CN-101084937-B Ginkgo leaves freezing-dried powder injection and preparation method thereof ZHENBAODAO PHARMACEUTICAL CO LTD HEILONGJIANG PROV 2010-06-30 CN disclosed
US-20090254120-A1 DEVICE AND METHOD FOR TREATING CENTRAL NERVOUS SYSTEM PATHOLOGY WAKE FOREST UNIVERSITY HEALTH SCIENCES 2009-10-08 US disclosed
WO-2009089435-A1 DEVICE AND METHOD FOR TREATING CENTRAL NERVOUS SYSTEM PATHOLOGY WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2009-07-16 WO disclosed
CN-101084937-A Ginkgo leaves freezing-dried powder injection and preparation method thereof HEILONGJIANG ZHENBAODAO PHARMA (CN) 2007-12-12 CN disclosed
US-5130119-A Sulfonamide or hydroxy fluorine substituted benzene for medical diagnosis SCHERING AKTIENGESELLSCHAFT (DE) 1992-07-14 US disclosed
US-4959612-A Method of heteronuclear decoupling in magnetic resonance spectroscopy, and device for determining a spectrum U.S. PHILIPS CORPORATION (US) 1990-09-25 US disclosed