Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27836486 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HPGDMAPTNPSR1HTT | |
| SCHEMBL9536173 | 0.74 | KMT2A (0.47) | PKMALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL76190 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HPGDSMN1; SMN2HTTPOLB | |
| SCHEMBL5250996 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2HTTPOLB | |
| SCHEMBL692795 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2MAPTHTT | |
| SCHEMBL733777 | 0.73 | KMT2A (0.69) | PKMALDH1A1MAPTNPSR1HTT | |
| SCHEMBL1044508 | 0.73 | ALDH1A1 (0.48) | PKMALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL28776030 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HPGDSMN1; SMN2HTTPOLB | |
| SCHEMBL5475470 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HPGDSMN1; SMN2HTTPOLB | |
| SCHEMBL29740651 | 0.73 | KMT2A (0.69) | PKMALDH1A1MAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101437826-A | Pentacyclic indole derivatives as antiviral agents | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-05-20 | — | — | CN | disclosed |