Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 2/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776242 | 0.89 | HRH3 (0.57) | HRH3GPR119EPHX2FPR2MLNR | |
| SCHEMBL2775119 | 0.85 | CCR1 (0.57) | EPHX2 | |
| SCHEMBL2775803 | 0.85 | CCR1 (0.55) | HRH3EPHX2NAMPTSRD5A1 | |
| SCHEMBL2780495 | 0.85 | CCR1 (0.55) | HRH3EPHX2NAMPTSRD5A1 | |
| SCHEMBL2779327 | 0.85 | DPP4 (0.46) | HRH3GPR119NAMPT | |
| SCHEMBL2777467 | 0.84 | HRH3 (0.56) | HRH3GPR119EPHX2FPR2MLNR | |
| SCHEMBL2777291 | 0.83 | EPHX2 (0.53) | EPHX2FPR2NAMPTSRD5A1PROKR1 | |
| SCHEMBL2774368 | 0.83 | EPHX2 (0.50) | EPHX2NAMPTSRD5A1 | |
| SCHEMBL2773428 | 0.83 | EPHX2 (0.49) | EPHX2FPR2NAMPTSRD5A1PROKR1 | |
| Hydrochloric Acid SCHEMBL2776091 | 0.81 | HRH3 (0.58) | HRH3GPR119EPHX2FPR2MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |