Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775803 | 1.00 | CCR1 (0.55) | CCR1KMT2ALMNATSHRNAMPT | |
| SCHEMBL2777291 | 0.89 | EPHX2 (0.53) | CCR1KMT2ALMNANAMPTSRD5A1 | |
| SCHEMBL2775119 | 0.88 | CCR1 (0.57) | CCR1EPHX2KCNH2 | |
| SCHEMBL2776968 | 0.88 | NAMPT (0.48) | CCR1NAMPTSRD5A1EPHX2HRH3 | |
| SCHEMBL2775706 | 0.88 | CCR1 (0.51) | CCR1KMT2ALMNANAMPTHRH3 | |
| SCHEMBL2773428 | 0.88 | EPHX2 (0.49) | CCR1NAMPTSRD5A1EPHX2 | |
| Hydrochloric Acid SCHEMBL2776549 | 0.87 | CCR1 (0.48) | CCR1KMT2ALMNATSHRNAMPT | |
| SCHEMBL2774368 | 0.86 | EPHX2 (0.50) | CCR1LMNANAMPTSRD5A1EPHX2 | |
| SCHEMBL2774053 | 0.85 | HRH3 (0.55) | NAMPTSRD5A1EPHX2HRH3 | |
| SCHEMBL2773036 | 0.85 | SRD5A1 (0.46) | CCR1KMT2ALMNANAMPTSRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |