Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 19/20 | 0.65 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.64 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.64 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 1/20 | 0.64 |
| ▸ | CSK | P41240 | 1/20 | 0.64 |
| ▸ | JAK3 | P52333 | 1/20 | 0.64 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4227010 | 0.96 | AURKA (0.68) | AURKAAURKBEGFRIGF1RFGFR1 | |
| Phosphoric Acid SCHEMBL27740608 | 0.95 | AURKA (0.67) | AURKAAURKBEGFRIGF1RFGFR1 | |
| SCHEMBL5042520 | 0.91 | AURKA (0.65) | AURKAAURKBEGFRIGF1RFGFR1 | |
| SCHEMBL5045797 | 0.91 | AURKA (0.73) | AURKAAURKBEGFRIGF1RFGFR1 | |
| SCHEMBL3884885 | 0.88 | AURKA (0.74) | AURKAAURKBEGFRIGF1RFGFR1 | |
| SCHEMBL6530607 | 0.88 | AURKA (0.74) | AURKAAURKBEGFRIGF1RFGFR1 | |
| SCHEMBL5045597 | 0.88 | AURKA (0.74) | AURKAAURKBEGFRIGF1RFGFR1 | |
| SCHEMBL5041746 | 0.88 | AURKA (0.74) | AURKAAURKBEGFRIGF1RFGFR1 | |
| Hydrochloric Acid SCHEMBL5045485 | 0.88 | AURKA (0.73) | AURKAAURKBEGFRIGF1RFGFR1 | |
| SCHEMBL5048641 | 0.86 | AURKA (0.87) | AURKAAURKBEGFRIGF1RFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101437577-A | Combination therapy for diseases involving angiogenesis | BAUSCH & LOMB (US) | 2009-05-20 | — | — | CN | disclosed |