Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 15/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592772 | 0.81 | ALDH1A1 (0.51) | HSD17B10KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL4274950 | 0.81 | HSD17B10 (0.49) | HSD17B10KDM4EALDH1A1HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL29204570 | 0.79 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL4275135 | 0.78 | KDM4E (0.51) | HSD17B10KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL4275027 | 0.78 | HSD17B10 (0.51) | HSD17B10KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL4284427 | 0.77 | HSD17B10 (0.50) | HSD17B10KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1402470 | 0.77 | KDM4E (0.62) | HSD17B10KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL4279374 | 0.77 | PDE4D (0.36) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL29204567 | 0.76 | DHODH (0.36) | HSD17B10KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1402313 | 0.76 | S1PR1 (0.64) | HSD17B10KDM4EALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309912-B | Oxazole compound and pharmaceutical composition | OTSUKA PHARMA CO LTD | 2013-09-25 | — | — | CN | disclosed |
| CN-101309912-A | Oxazole compound and pharmaceutical composition | OTSUKA PHARMA CO LTD (JP) | 2008-11-19 | — | — | CN | disclosed |